This study explores the effects of dynamic and static loading on rock bolt performance a key factor in maintaining the structural safety of coal mine roadways susceptible to coal bursts.Employing a house-made load frame to simulate various failure scenarios, pretension-impact-pull tests on rock bolts were conducted to scrutinize their dynamic respo
PML nuclear bodies and neuronal intranuclear inclusion in polyglutamine diseases
In polyglutamine diseases, accumulation in the nucleus of mutant proteins induces the formation of neuronal intranuclear inclusions (NIIs).The nucleus is compartmentalized into structural and functional domains, which are involved in NII formation.Promyelocytic leukemia protein (PML), a major component of nuclear bodies, and mSin3A, a component of
A WeChat-Based Mobile Platform for Perioperative Health Education for Gastrointestinal Surgery
Appropriately instructing and guiding patients before and after surgery is essential for their successful recovery.In recent years, however, the development of the enhanced recovery after surgery (ERAS) protocol has restricted the opportunity for healthcare professionals to spend time with their patients before and after surgery because of efficien
Managing chronic thromboembolic pulmonary hypertension: pharmacological treatment options
Chronic thromboembolic pulmonary hypertension (CTEPH) is a life-threatening condition in which organised thrombi obstruct the pulmonary LONG SLEEVE TOPS vessels, causing increased pulmonary vascular resistance, progressive pulmonary hypertension (PH) and right heart failure.The treatment of choice is pulmonary endarterectomy, which restores pulmona